GO:0035195 biological_process gene silencing by miRNA
| PAG Title | GO:0035195 biological_process gene silencing by miRNA |
| PAG ID | TAX022759 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endolytic cleavage of mRNA cleavage or translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA. |
| Species | Homo sapiens |
| nCoCo Score | 177 |
| Base PAG ID | TAX022759 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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